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The University of Pennsylvania has long been the dominant institution in the area and was instrumental in coining the name “University City” as part of a 1950s urban-renewal and gentrification effort. Today, Drexel University and the University of the Sciences also call University City home. The neighborhood has an interesting, eclectic vibe with Victorian and early 20th century housing, as well as brand new developments popping up as students and residents alike move into the area.

The eastern side of University City is home to the Penn and Drexel campuses, several medical institutions, independent centers of scientific research, 30th Street Station, and the Cira Centre.

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